Adipokinetic Hormone II (Locusta migratoria)
Modify Date: 2025-08-25 13:02:47
Adipokinetic Hormone II (Locusta migratoria) structure
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Common Name | Adipokinetic Hormone II (Locusta migratoria) | ||
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| CAS Number | 98968-94-6 | Molecular Weight | 903.98000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H57N11O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Adipokinetic Hormone II (Locusta migratoria)Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)[1][3]. |
| Name | L-Tryptophanamide, 5-oxo-L-prolyl-L-leucyl-L-asparaginyl-L-phenylalanyl-L-seryl-L-alanylglycyl |
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| Synonym | More Synonyms |
| Description | Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)[1][3]. |
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| Related Catalog | |
| In Vitro | Adipokinetic hormone II (Locusta migratoria) (radiolabeled; 1 pmol in 10 μL of 10% methanol; 30 min on ice, and repeated for 2 h at 30 ℃) shows no association with one of the larger protein components, indicating a lack of separate transporting or carrier protein in the hemolymph[1]. Adipokinetic hormones (AKHs) are known to be involved in insect immunity and shows the mechanism of metabolic stimulation, leading a significant increase in carbon dioxide production, and efficacy increase of toxins produced by I. fumosorosea in the cockroach's body[2]. Adipokinetic hormone II is more effective than hormone I in bringing about an accumulation of cAMP in the fat body[4]. |
| In Vivo | Adipokinetic hormone II (Locusta migratoria) (1 pmol in 10 μL of 10% methanol; injection) plays its own biol. role in the overall syndrome of insect flight, with different half-lives of 40 min and 37 min during rest and flight, respectively[1]. |
| Molecular Formula | C43H57N11O11 |
|---|---|
| Molecular Weight | 903.98000 |
| Exact Mass | 903.42400 |
| PSA | 355.00000 |
| LogP | 1.14140 |
| InChIKey | KMVRKMSUXFKTDO-UHFFFAOYSA-N |
| SMILES | CC(C)CC(NC(=O)C1CCC(=O)N1)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)NC(C)C(=O)NCC(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O |
| Chromatophorotropin, red-pigment-concentrating (Pandalus borealis) 6-L-alanine- |
| ADIPOKINETIC HORMONE II (LOCUSTA MIGRATORIA) |
| Lom-AKH-2 |
| ADIPOKINETIC HORMONE II |
| Adipokinetic hormone II (Locusta migratoria) |
| Locust adipokinetic hormone II |
| Lom-AKH-II |