Trandolaprilat Monohydrate

Modify Date: 2024-02-12 10:16:59

Trandolaprilat Monohydrate structure	Common Name	Trandolaprilat Monohydrate
	CAS Number	951393-55-8	Molecular Weight	420.49900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₂N₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Trandolaprilat Monohydrate

Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate hydrate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity[1][2].

Name	Trandolaprilat Monohydrate
Synonym	More Synonyms

Description	Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate hydrate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
Target	Human Endogenous Metabolite
References	[1]. Al-Hawash LA, et al. Stability-indicating HPLC determination of trandolapril in bulk drug and pharmaceutical dosage forms. Int J Anal Chem. 2015;2015:820517. [2]. Millet D, et al. Effects of angiotensins on cellular hypertrophy and c-fos expression in cultured arterial smooth muscle cells. Eur J Biochem. 1992 Jun 1;206(2):367-72.

Molecular Formula	C₂₂H₃₂N₂O₆
Molecular Weight	420.49900
Exact Mass	420.22600
PSA	116.17000
LogP	2.55930

(2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid, hydrate

Trandolaprilate Monohydrate

Trandolaprilat Monohydrate

Use of Trandolaprilat Monohydrate

Names

Trandolaprilat Monohydrate Biological Activity

Chemical & Physical Properties

Synonyms