6-O-Methacrylate

Modify Date: 2025-08-25 09:54:00

6-O-Methacrylate Structure
6-O-Methacrylate structure
 Common Name 6-O-Methacrylate
CAS Number 950685-51-5 Molecular Weight 450.48
Density N/A Boiling Point N/A
Molecular Formula C23H30O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 6-O-Methacrylate


6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity[1][2].

 Names

Name 6-O-Methacryloyltrilobolide
Synonym More Synonyms

 6-O-Methacrylate Biological Activity

Description 6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity[1][2].
Related Catalog
In Vitro 6-O-Methacrylate (10 μg/mL) shows anti-TMV activities in the pretreated tobacco plants with inhibition rate of 59.6%[2].
References

[1]. That QT, et, al. Wedelolides A and B: novel sesquiterpene delta-lactones, (9R)-eudesman-9,12-olides, from Wedelia trilobata. J Org Chem. 2007 Sep 14;72(19):7102-5.

[2]. Li Y, et, al. Eudesmanolides from Wedelia trilobata (L.) Hitchc. as potential inducers of plant systemic acquired resistance. J Agric Food Chem. 2013 Apr 24;61(16):3884-90.

 Chemical & Physical Properties

Molecular Formula C23H30O9
Molecular Weight 450.48

 Synonyms

MFCD34471092
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