Kazusamycin A

Modify Date: 2025-09-03 18:09:00

Kazusamycin A Structure
Kazusamycin A structure
Common Name Kazusamycin A
CAS Number 92090-94-3 Molecular Weight 556.73
Density 1.109±0.06 g/cm3 (20 °C, 760 mmHg) Boiling Point 761.5±60.0 °C (760 mmHg)
Molecular Formula C33H48O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Kazusamycin A


Kazusamycin A (PD-114721) is an antitumor antibiotic. Kazusamycin A can be isolated from fermentation beers of a previously unknown actinomycete[1].

 Names

Name 2,10,12,16,18-Nonadecapentaenoic acid, 19-[(2S,3S)-3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, (2E,5S,6R,7S,9S,10E,12E,15R,16Z,18E)
Synonym More Synonyms

 Kazusamycin A Biological Activity

Description Kazusamycin A (PD-114721) is an antitumor antibiotic. Kazusamycin A can be isolated from fermentation beers of a previously unknown actinomycete[1].
Related Catalog
References

[1]. Roberts BJ, et al. In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721). Cancer Chemother Pharmacol. 1986;16(2):95-101.  

 Chemical & Physical Properties

Density 1.109±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point 761.5±60.0 °C (760 mmHg)
Molecular Formula C33H48O7
Molecular Weight 556.73
Exact Mass 556.34000
PSA 121.13000
LogP 5.75710
InChIKey KZMHNEBMQDBQND-LBNZKSCFSA-N
SMILES CCC(C=CC1OC(=O)C=CC1C)=CC(C)CC=CC(C)=CC(CO)C(=O)C(C)C(O)C(C)CC(C)=CC(=O)O

 Synonyms

Antibiotic CL 1957B
KAZUSAMYCIN A (KAZUSAMYCIN, HYDROXYLEPTOMYCIN B, HYDROXYELACTOCIN, ANTIBIOTIC CL 1957B, ANTIBIOTIC PD 114721)
Antibiotic 81-484
Kazusamycin
CL 1957B
Kazusamycin A
KAZUSAMYCIN A
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