SHP 244

Modify Date: 2025-11-26 10:47:45

SHP 244 Structure
SHP 244 structure
Common Name SHP 244
CAS Number 902891-37-6 Molecular Weight 432.864
Density N/A Boiling Point N/A
Molecular Formula C23H17ClN4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SHP 244


SHP244 is a distinct, allosteric site 2 SHP2 inhibitor with IC50 of 60 uM (SHP2 1-525), equipotent on the double mutant (SHP2T253M/Q257L IC50=68 uM), and selective over the phosphatase domain (SHP2 PTP IC50>100 uM).

 Names

Name SHP 244

 SHP 244 Biological Activity

Description SHP244 is a distinct, allosteric site 2 SHP2 inhibitor with IC50 of 60 uM (SHP2 1-525), equipotent on the double mutant (SHP2T253M/Q257L IC50=68 uM), and selective over the phosphatase domain (SHP2 PTP IC50>100 uM).
References References 1. Fodor M, et al. ACS Chem Biol. 2018 Jan 18. doi: 10.1021/acschembio.7b00980. View Related Products by Target Protein Phosphatase/PTP

 Chemical & Physical Properties

Molecular Formula C23H17ClN4O3
Molecular Weight 432.864
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