Hydroxyethyl cellulose

Modify Date: 2024-01-02 21:43:50

Hydroxyethyl cellulose structure	Common Name	Hydroxyethyl cellulose
	CAS Number	9004-62-0	Molecular Weight	154.25100
	Density	0.75 g/mL at 25ºC(lit.)	Boiling Point	N/A
	Molecular Formula	C₄H₁₀O₂S₂	Melting Point	288-290ºC (dec.)
	MSDS	Chinese USA	Flash Point	N/A

Use of Hydroxyethyl cellulose

Hydroxyethyl cellulose is a non-ionic, water soluble, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.

Name	Hydroxyethyl Cellulose
Synonym	More Synonyms

Description	Hydroxyethyl cellulose is a non-ionic, water soluble, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
In Vitro	Stabilization of graphene oxide in physiological solution is performed using hydroxyethyl cellulose to make the resultant nanohybrid suitable for targeted drug delivery purposes. Hydroxyethyl cellulose effectively stabilizes graphene oxid in electrolyte solutions and the mechanism of stabilization appears to be depended on hydroxyethyl cellulose content. Hydroxyethyl cellulose content in the nanohybrid plays an important role in final application to make it applicable either as a carrier for controllable drug release or as a folate-targeted drug carrier[1]. Hydroxyethyl cellulose shows superior cryoprotective effects on LDH during freeze thawing, and considerable lyoprotective effects during the freeze drying process. Annealing has limited influence on the stabilizing effect of hydroxyethyl cellulose. The extensive reconstitution times of the hydroxyethyl cellulose lyophilisates could be greatly improved by incorporation of the surfactant Tween 80 into the formulations prior to freeze drying[2].
References	[1]. Mianehrow H, et al. Graphene-oxide stabilization in electrolyte solutions using hydroxyethyl cellulose for drug delivery application. Int J Pharm. 2015 Apr 30;484(1-2):276-82. [2]. Al-Hussein A, et al. Investigation of the stabilizing effects of hydroxyethyl cellulose on LDH during freeze drying and freeze thawing cycles. Pharm Dev Technol. 2015 Jan;20(1):50-9.

Density	0.75 g/mL at 25ºC(lit.)
Melting Point	288-290ºC (dec.)
Molecular Formula	C₄H₁₀O₂S₂
Molecular Weight	154.25100
Exact Mass	154.01200
PSA	91.06000
LogP	0.35240
Storage condition	room temp
Stability	Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides
Water Solubility	H2O: ≤5 wt. % at 20 °C

Hydroxyethyl cellulose MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FJ5958000

CHEMICAL NAME :: Cellulose, 2-hydroxyethyl ether

CAS REGISTRY NUMBER :: 9004-62-0

LAST UPDATED :: 199710

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 5100 mg/kg/6D-I

TOXIC EFFECTS :: Brain and Coverings - increased intracranial pressure Behavioral - somnolence (general depressed activity) Vascular - change in plasma or blood volume

REFERENCE :: NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 317,964,1987 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 500 mg/kg

SEX/DURATION :: female 3-7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: ANANAU Anatomischer Anzeiger. (VEB Gustav Fischer Verlag, Postfach 176, Jena DDR-6900, Ger. Dem. Rep.) V.1- 1886- Volume(issue)/page/year: 149,282,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82127 No. of Facilities: 8381 (estimated) No. of Industries: 70 No. of Occupations: 62 No. of Employees: 95547 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82127 No. of Facilities: 27127 (estimated) No. of Industries: 167 No. of Occupations: 124 No. of Employees: 749900 (estimated) No. of Female Employees: 369916 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	T
Risk Phrases	R23/24/25
Safety Phrases	26-36-45-24/25-22
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	FJ5958000
HS Code	3912390000

HS Code	3912390000

Effects of different amine fluoride concentrations on enamel remineralization.

J. Dent. 40(9) , 750-5, (2012)

The aim of this study was to investigate the effects of decreasing fluoride concentrations on repeated demineralizing challenges on human enamel.In 24 teeth, 3mm×3mm windows were prepared on the bucca...

Disposable polyester-toner electrophoresis microchips for DNA analysis.

Analyst 137(11) , 2692-8, (2012)

Microchip electrophoresis has become a powerful tool for DNA separation, offering all of the advantages typically associated with miniaturized techniques: high speed, high resolution, ease of automati...

Effect of fluoride, lesion baseline severity and mineral distribution on lesion progression.

Caries Res. 46(1) , 23-30, (2012)

The present study investigated the effects of fluoride (F) concentration, lesion baseline severity (ΔZ(base)) and mineral distribution on lesion progression. Artificial caries lesions were created usi...

MFCD00072770

2,2'-Disulfanediyldiethanol

EINECS 618-387-5

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Hydroxyethyl cellulose
Price: ￥128.0/250g ￥398.0/1kg ￥478.0/1kg ￥128.0/250g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Hydroxyethyl Cellulose
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Hydroxyethyl Cellulose
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Hydroxyethyl Cellulose
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Hydroxyethyl cellulose

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