Mmv665916

Modify Date: 2025-08-25 13:03:54

Mmv665916 Structure
Mmv665916 structure
Common Name Mmv665916
CAS Number 896356-25-5 Molecular Weight 353.37
Density N/A Boiling Point N/A
Molecular Formula C19H19N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mmv665916


MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 µM and presents the high selectivity index (SI>250)[1].

 Names

Name MMV665916

 Mmv665916 Biological Activity

Description MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 µM and presents the high selectivity index (SI>250)[1].
Related Catalog
References

[1]. Laura Mourot, et al.  Structure-activity relationship and molecular modelling studies of quinazolinedione derivatives MMV665916 as potential antimalarial agent. Bioorg Med Chem. 2021 Dec 1;51:116513.

 Chemical & Physical Properties

Molecular Formula C19H19N3O4
Molecular Weight 353.37
InChIKey GONCPXNUBXWDEU-UHFFFAOYSA-N
SMILES COc1ccccc1CNC(=O)CCn1c(=O)[nH]c2ccccc2c1=O
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