MLS1082
Modify Date: 2025-08-23 18:29:45
MLS1082 structure
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Common Name | MLS1082 | ||
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| CAS Number | 883958-36-9 | Molecular Weight | 385.458 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 520.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C24H23N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 268.4±32.9 °C | |
Use of MLS1082MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies. |
| Name | 2-Cyclohexyl-10-methyl-3-phenyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione |
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| Synonym | More Synonyms |
| Description | MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies. |
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| References | References 1. Luderman KD, et al. Mol Pharmacol. 2018 Aug 1. pii: mol.118.113175. View Related Products by Target Dopamine Receptor |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 520.1±60.0 °C at 760 mmHg |
| Molecular Formula | C24H23N3O2 |
| Molecular Weight | 385.458 |
| Flash Point | 268.4±32.9 °C |
| Exact Mass | 385.179016 |
| LogP | 2.78 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.688 |
| InChIKey | HZGMAMIIHBRAAR-UHFFFAOYSA-N |
| SMILES | Cn1c2ccccc2c(=O)c2c(=O)n(-c3ccccc3)c(C3CCCCC3)nc21 |
| Pyrimido[4,5-b]quinoline-4,5(3H,10H)-dione, 2-cyclohexyl-10-methyl-3-phenyl- |
| 2-Cyclohexyl-10-methyl-3-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione |
| 2-Cyclohexyl-10-methyl-3-phenyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione |