Foxy 5 TFA

Modify Date: 2024-01-19 09:02:28

Foxy 5 TFA structure	Common Name	Foxy 5 TFA
	CAS Number	881188-51-8	Molecular Weight	694.775
	Density	1.4±0.1 g/cm3	Boiling Point	1244.1±65.0 °C at 760 mmHg
	Molecular Formula	C₂₆H₄₂N₆O₁₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	706.2±34.3 °C

Use of Foxy 5 TFA

Foxy-5 is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 is a WNT5A agonist and effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1][2].

Name	FOXY-5
Synonym	More Synonyms

Description	Foxy-5 is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 is a WNT5A agonist and effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt
Target	WNT5A[1]
In Vivo	Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1]. Foxy-5 reduces the number of colonic cancer stem cells in a xenograft mouse model of human colonic cancer[2].
References	[1]. Canesin G, et al. Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model. PLoS One. 2017 Sep 8;12(9):e0184418. [2]. Osman J, et al. The WNT5A Agonist Foxy5 Reduces the Number of Colonic Cancer Stem Cells in a Xenograft Mouse Model of Human Colonic Cancer. Anticancer Res. 2019 Apr;39(4):1719-1728.

Density	1.4±0.1 g/cm3
Boiling Point	1244.1±65.0 °C at 760 mmHg
Molecular Formula	C₂₆H₄₂N₆O₁₂S₂
Molecular Weight	694.775
Flash Point	706.2±34.3 °C
Exact Mass	694.230225
LogP	0.62
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.562