Anti-inflammatory agent 42

Modify Date: 2025-11-19 15:46:27

Anti-inflammatory agent 42 Structure
Anti-inflammatory agent 42 structure
Common Name Anti-inflammatory agent 42
CAS Number 877468-30-9 Molecular Weight 328.39
Density 1.4±0.1 g/cm3 Boiling Point 579.8±53.0 °C at 760 mmHg
Molecular Formula C20H12N2OS Melting Point 213-215 °C(Solv: acetic acid (64-19-7))
MSDS N/A Flash Point 304.5±30.9 °C

 Use of Anti-inflammatory agent 42


Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent. Anti-inflammatory agent 42 shows excellent inhibition on the expression of TNF-α and IL-6 in LPS (HY-D1056)-stimulated macrophages[1].

 Names

Name WAY-620520
Synonym More Synonyms

 Anti-inflammatory agent 42 Biological Activity

Description Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent. Anti-inflammatory agent 42 shows excellent inhibition on the expression of TNF-α and IL-6 in LPS (HY-D1056)-stimulated macrophages[1].
Related Catalog
In Vitro Anti-inflammatory agent 42 (Compound 10j; 10 μM; 2 h) 抑制 LPS 诱导的 RAW 264.7 巨噬细胞 TNF-α 和 IL-6 分泌[1]。
References

[1]. Hu J, et al. Synthesis and biological evaluation of novel thiazolidinone derivatives as potential anti-inflammatory agents. Eur J Med Chem. 2013 Jun;64:292-301.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 579.8±53.0 °C at 760 mmHg
Melting Point 213-215 °C(Solv: acetic acid (64-19-7))
Molecular Formula C20H12N2OS
Molecular Weight 328.39
Flash Point 304.5±30.9 °C
Exact Mass 328.067047
LogP 6.16
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.752

 Synonyms

2-Naphthalen-1-ylmethylene-benzo[4,5]imidazo[2,1-b]thiazol-3-one
Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-(1-naphthylmethylene)-
(2Z)-2-(1-Naphthylmethylene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-(1-naphthalenylmethylene)-, (2Z)-
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