M1001

Modify Date: 2025-08-25 17:36:28

M1001 Structure
M1001 structure
Common Name M1001
CAS Number 874590-32-6 Molecular Weight 327.40
Density N/A Boiling Point N/A
Molecular Formula C17H17N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of M1001


M1001 is a weak agonist of HIF-2α, directly binds to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 enhances the stabilities of HIF-2α-ARNT complex[1].

 Names

Name M1001

 M1001 Biological Activity

Description M1001 is a weak agonist of HIF-2α, directly binds to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 enhances the stabilities of HIF-2α-ARNT complex[1].
Related Catalog
Target

Kd: 667 nM (HIF-2α)[1]

References

[1]. Wu D, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Feb 25.

 Chemical & Physical Properties

Molecular Formula C17H17N3O2S
Molecular Weight 327.40
Storage condition 2-8°C
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