MEDICA 16

Modify Date: 2025-08-30 20:34:24

MEDICA 16 structure	Common Name	MEDICA 16
	CAS Number	87272-20-6	Molecular Weight	342.513
	Density	1.0±0.1 g/cm3	Boiling Point	485.9±18.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₃₈O₄	Melting Point	154-159ºC
	MSDS	Chinese USA	Flash Point	261.8±17.7 °C

Use of MEDICA 16

MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle, and this reduction is accompanied by an increase in insulin sensitivity. MEDICA16 is a selective agonist for GPR40 as well as selective partial agonists for GPR120[1][2].

Name	3,3,14,14-tetramethylhexadecanedioic acid
Synonym	More Synonyms

Description	MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle, and this reduction is accompanied by an increase in insulin sensitivity. MEDICA16 is a selective agonist for GPR40 as well as selective partial agonists for GPR120[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPR120 Signaling Pathways >> Metabolic Enzyme/Protease >> ATP Citrate Lyase Signaling Pathways >> GPCR/G Protein >> GPR40 Research Areas >> Metabolic Disease
References	[1]. Atkinson LL, et al. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. 2002;51(5):1548-1555. [2]. Hara T, Hirasawa A, Sun Q, et al. Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch Pharmacol. 2009;380(3):247-255.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> GPR120

Signaling Pathways >> Metabolic Enzyme/Protease >> ATP Citrate Lyase

Signaling Pathways >> GPCR/G Protein >> GPR40

Research Areas >> Metabolic Disease

References

[1]. Atkinson LL, et al. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. 2002;51(5):1548-1555.

[2]. Hara T, Hirasawa A, Sun Q, et al. Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch Pharmacol. 2009;380(3):247-255.

Density	1.0±0.1 g/cm3
Boiling Point	485.9±18.0 °C at 760 mmHg
Melting Point	154-159ºC
Molecular Formula	C₂₀H₃₈O₄
Molecular Weight	342.513
Flash Point	261.8±17.7 °C
Exact Mass	342.277008
PSA	74.60000
LogP	6.44
Vapour Pressure	0.0±2.6 mmHg at 25°C
Index of Refraction	1.474
InChIKey	HYSMCRNFENOHJH-UHFFFAOYSA-N
SMILES	CC(C)(CCCCCCCCCCC(C)(C)CC(=O)O)CC(=O)O

MEDICA 16 MSDS(Chinese)

HS Code	2917190090

1,1,14,14-Tetra...

CAS#:87272-21-7

MEDICA 16

CAS#:87272-20-6

Literature: WO2008/18877 A1, ; Page/Page column 20; 40-41 ;

Precursor 1
CAS#:87272-21-7 1,1,14,14-Tetra...
DownStream 0

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

3,3,14,14-Tetramethylhexanedecanedioic acid

3,3,14,14-tetramethyl-1,16-hexadecanedioic acid

MEDICA 16

Medic-16

3,3,14,14-tetramethyl-hexadecanedioic acid

3,3,14,14-Tetramethylhexadecanedioic acid

Hexadecandioic acid,3,3,14,14-tetramethyl

3,3,14,14-tetramethyl-hexadecane-1,16-dioic acid

Hexadecanedioic acid, 3,3,14,14-tetramethyl-

MFCD00797684

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MEDICA 16
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MEDICA 16
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: MEDICA 16
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.