Rosomidnar

Modify Date: 2024-04-03 04:23:11

Rosomidnar structure	Common Name	Rosomidnar
	CAS Number	871597-03-4	Molecular Weight	7220.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂₇H₂₉₁O₁₄₁P₂₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Rosomidnar

PNT100 is a 24-base, chemically unmodified DNA oligonucleotide sequence that is complementary to the regulatory region upstream of the BCL-2 gene. Exposure of tumor cells to PNT100 results in suppression of proliferation and cell death.

Name	Rosomidnar

Description	PNT100 is a 24-base, chemically unmodified DNA oligonucleotide sequence that is complementary to the regulatory region upstream of the BCL-2 gene. Exposure of tumor cells to PNT100 results in suppression of proliferation and cell death.
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
References	[1]. Rodrigueza WV, Woolliscroft MJ, Ebrahim AS, et al. Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide. Cancer Chemother Pharmacol. 2014;74(1):151-166. [2]. Westin J, Maris MB, Jacobson CA, et al. Safety and Efficacy of a DNA Oligonucleotide Therapy in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2022;22(1):52-59.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Bcl-2 Family

Research Areas >> Cancer

References

[1]. Rodrigueza WV, Woolliscroft MJ, Ebrahim AS, et al. Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide. Cancer Chemother Pharmacol. 2014;74(1):151-166.

[2]. Westin J, Maris MB, Jacobson CA, et al. Safety and Efficacy of a DNA Oligonucleotide Therapy in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2022;22(1):52-59.

Molecular Formula	C₂₂₇H₂₉₁O₁₄₁P₂₃
Molecular Weight	7220.63

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Rosomidnar

Use of Rosomidnar

Names

Rosomidnar Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.