(1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one

Modify Date: 2024-01-08 19:16:59

(1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one Structure
(1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one structure
Common Name (1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one
CAS Number 869367-33-9 Molecular Weight 372.82100
Density N/A Boiling Point N/A
Molecular Formula C20H18ClFN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name (4E)-8-chloro-4-(dimethylaminomethylene)-1-(2-fluoro-6-methoxy-ph enyl)-3H-2-benzazepin-5-one
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C20H18ClFN2O2
Molecular Weight 372.82100
Exact Mass 372.10400
PSA 41.90000
LogP 3.40250

 Synthetic Route

~84%

(1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one Structure

(1E,4E)-8-chlor...

CAS#:869367-33-9

Literature: MILLENNIUM PHARMACEUTICALS, INC.; ARMITAGE, Ian; COOPER, Martin, I.; EDDLESTON, Mark, D.; FAIBER, Neil, C.; MCCUBBIN, Quentin, J.; WATT, Stephen, W. Patent: WO2011/103089 A1, 2011 ; Location in patent: Page/Page column 44-45 ; WO 2011/103089 A1

~%

(1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one Structure

(1E,4E)-8-chlor...

CAS#:869367-33-9

Literature: MILLENNIUM PHARMACEUTICALS, INC.; ARMITAGE, Ian; COOPER, Martin, I.; EDDLESTON, Mark, D.; FAIBER, Neil, C.; MCCUBBIN, Quentin, J.; WATT, Stephen, W. Patent: WO2011/103089 A1, 2011 ; WO 2011/103089 A1

~%

(1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one Structure

(1E,4E)-8-chlor...

CAS#:869367-33-9

Literature: MILLENNIUM PHARMACEUTICALS, INC.; ARMITAGE, Ian; COOPER, Martin, I.; EDDLESTON, Mark, D.; FAIBER, Neil, C.; MCCUBBIN, Quentin, J.; WATT, Stephen, W. Patent: WO2011/103089 A1, 2011 ; WO 2011/103089 A1

~%

(1E,4E)-8-chloro-4-((dimethylamino)Methylene)-1-(2-fluoro-6-Methoxyphenyl)-3,4-dihydrobenzo[c]azepin-5-one Structure

(1E,4E)-8-chlor...

CAS#:869367-33-9

Literature: MILLENNIUM PHARMACEUTICALS, INC.; ARMITAGE, Ian; COOPER, Martin, I.; EDDLESTON, Mark, D.; FAIBER, Neil, C.; MCCUBBIN, Quentin, J.; WATT, Stephen, W. Patent: WO2011/103089 A1, 2011 ; WO 2011/103089 A1

 Synonyms

3H-2-Benzazepine,4,5-dibromo-8-chloro-4,5-dihydro-1-phenyl
8-chloro-4,5-dibromo-4,5-dihydro-1-phenyl-3H-2-benzazepine
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