HAEGTFTSDVS

Modify Date: 2024-04-01 19:58:52

HAEGTFTSDVS Structure
HAEGTFTSDVS structure
Common Name HAEGTFTSDVS
CAS Number 864915-61-7 Molecular Weight 1150.18
Density N/A Boiling Point N/A
Molecular Formula C48H71N13O20 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HAEGTFTSDVS


HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.

 Names

Name HAEGTFTSDVS

 HAEGTFTSDVS Biological Activity

Description HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
Related Catalog
In Vitro The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2].
References

[1]. US20120264685

[2]. US9738697

 Chemical & Physical Properties

Molecular Formula C48H71N13O20
Molecular Weight 1150.18
InChIKey DVFFCJRYQFXVGO-QZDJTBDFSA-N
SMILES CC(NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NC(C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NC(CO)C(=O)O)C(C)C)C(C)O)C(C)O
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