HAEGTFTSDVS structure
|
Common Name | HAEGTFTSDVS | ||
|---|---|---|---|---|
| CAS Number | 864915-61-7 | Molecular Weight | 1150.18 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C48H71N13O20 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HAEGTFTSDVSHAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide. |
| Name | HAEGTFTSDVS |
|---|
| Description | HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide. |
|---|---|
| Related Catalog | |
| In Vitro | The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2]. |
| References |
[1]. US20120264685 [2]. US9738697 |
| Molecular Formula | C48H71N13O20 |
|---|---|
| Molecular Weight | 1150.18 |
| InChIKey | DVFFCJRYQFXVGO-QZDJTBDFSA-N |
| SMILES | CC(NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NC(C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NC(CO)C(=O)O)C(C)C)C(C)O)C(C)O |