TM6089

Modify Date: 2024-01-11 16:16:18

TM6089 Structure
TM6089 structure
Common Name TM6089
CAS Number 863421-32-3 Molecular Weight 306.34
Density N/A Boiling Point N/A
Molecular Formula C13H14N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TM6089


TM6089 is a unique Prolyl Hydroxylase (PHD) inhibitor which stimulates HIF activity without iron chelation and induces angiogenesis and exerts organ protection against ischemia. Local administration of TM6089 enhances angiogenesis, and oral administration stimulates HIF activity in transgenic rats expressing a hypoxia-responsive reporter vector[1].

 Names

Name TM6089

 TM6089 Biological Activity

Description TM6089 is a unique Prolyl Hydroxylase (PHD) inhibitor which stimulates HIF activity without iron chelation and induces angiogenesis and exerts organ protection against ischemia. Local administration of TM6089 enhances angiogenesis, and oral administration stimulates HIF activity in transgenic rats expressing a hypoxia-responsive reporter vector[1].
Related Catalog
References

[1]. Nangaku M, et al. A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2548-54.

 Chemical & Physical Properties

Molecular Formula C13H14N4O3S
Molecular Weight 306.34