(S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

Modify Date: 2024-01-18 14:28:11

(S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione Structure
(S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione structure
Common Name (S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
CAS Number 84017-99-2 Molecular Weight 422.43100
Density N/A Boiling Point N/A
Molecular Formula C23H22N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name (4S)-11-(Dimethoxymethyl)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]i ndolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C23H22N2O6
Molecular Weight 422.43100
Exact Mass 422.14800
PSA 99.88000
LogP 2.37100

 Synthetic Route

~84%

(S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione Structure

(S)-11-Dimethox...

CAS#:84017-99-2

Literature: Giannini, Giuseppe; Marzi, Mauro; Cabri, Walter; Marastoni, Elena; Battistuzzi, Gianfranco; Vesci, Loredana; Pisano, Claudio; Beretta, Giovanni Luca; Cesare, Michelandrea De; Zunino, Franco Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 9 p. 2910 - 2915

~%

(S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione Structure

(S)-11-Dimethox...

CAS#:84017-99-2

Literature: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. Patent: WO2009/16068 A1, 2009 ; Location in patent: Page/Page column 8 ;

~16%

(S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione Structure

(S)-11-Dimethox...

CAS#:84017-99-2

Literature: Sawada; Nokata; Furuta; Yokokura; Miyasaka Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 10 p. 2574 - 2580

~%

(S)-11-DimethoxyMethyl-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione Structure

(S)-11-Dimethox...

CAS#:84017-99-2

Literature: THRESHOLD PHARMACEUTICALS, INC.; CAI, Xiaohong; DUAN, Jian-Xin; MATTEUCCI, Mark; CAO, Yeyu; JIAO, Hailong Patent: WO2010/148138 A2, 2010 ; Location in patent: Page/Page column 68-69 ; WO 2010/148138 A2

 Synonyms

7-dimethoxymethyl-1,3,5-cycloheptatriene
cyclohepta-2,4,6-trienecarbaldehyde dimethylacetal
Cycloheptatrien-7-carboxaldehyd-dimethylacetal
Cyclohepta-2,4,6-triencarbaldehyd-dimethylacetal
Cyclohepta-2,4,6-trien-1-carbaldehyd-dimethylacetal
7-formyl-camptothecin dimethylacetal
7-Dimethoxymethylcycloheptatrien
7-dimethyl-acetal camptothecin
7-Dimethoxymethylcamptothecin
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