GLX351322
Modify Date: 2025-08-25 13:13:23
GLX351322 structure
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Common Name | GLX351322 | ||
|---|---|---|---|---|
| CAS Number | 835598-94-2 | Molecular Weight | 431.505 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 665.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C21H25N3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 356.3±31.5 °C | |
Use of GLX351322GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M. |
| Name | GLX351322 |
|---|---|
| Synonym | More Synonyms |
| Description | GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M. |
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| Related Catalog | |
| Target |
IC50: 5 μ M (NOX4, cell assay), 40 μM (NOX2, cell assay)[1] |
| In Vitro | GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells (IC50, 40 μM). |
| In Vivo | GLX351322 (3.8 mg/kg/day, p.o.) ameliorates HFD-induced hyperglycemia in mice[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 665.5±55.0 °C at 760 mmHg |
| Molecular Formula | C21H25N3O5S |
| Molecular Weight | 431.505 |
| Flash Point | 356.3±31.5 °C |
| Exact Mass | 431.151489 |
| LogP | 4.10 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.625 |
| Storage condition | 2-8℃ |
| Ethyl 2-({[4-(2-furoyl)-1-piperazinyl]acetyl}amino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate |
| 4H-Cyclopenta[b]thiophene-3-carboxylic acid, 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-, ethyl ester |