Docosahexaenoic acid ethyl ester

Modify Date: 2025-08-24 16:35:38

Docosahexaenoic acid ethyl ester Structure
Docosahexaenoic acid ethyl ester structure
Common Name Docosahexaenoic acid ethyl ester
CAS Number 81926-94-5 Molecular Weight 356.54
Density N/A Boiling Point N/A
Molecular Formula C24H36O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Docosahexaenoic acid ethyl ester


Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects[1][2].

 Names

Name ethyl (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate
Synonym More Synonyms

 Docosahexaenoic acid ethyl ester Biological Activity

Description Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects[1][2].
Related Catalog
In Vivo Docosahexaenoic acid ethyl ester (DHA-EE) (500 mg/kg; IP; once daily for 7 days) enhances 6-OHDA-induced reduction of striatal dopamine level[2].
References

[1]. Dahms I, et al. Safety of docosahexaenoic acid (DHA) administered as DHA ethyl ester in a 9-month toxicity study in dogs. Food Chem Toxicol. 2016;92:50-57.

[2]. Kabuto H, et al. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Neurochem Res. 2009;34(7):1299-1303.

 Chemical & Physical Properties

Molecular Formula C24H36O2
Molecular Weight 356.54
Exact Mass 355.26400
PSA 40.13000
LogP 5.99440

 Synthetic Route

 Synonyms

cis-4,7,10,13,16,19-docosahexaneoic acid ethyl ester
ethyl-ester all cis 4,7,10,13,16,19-docosahexaenoate
(all-Z)
DHA ethyl ester
4,7,10,13,16,19-docosahexaenoic acid ethyl ester
Doconexent [inn]
Docosahexaenoic Acid Ethyl Ester
4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid ethyl ester
(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid Ethyl Ester-d5
Ethyl (all-Z)-docosa-4,7,10,13,16,19-hexaenoate
Docosahexanoic acid-[D5]-ethylester
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