Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide trifluoroacetate salt

Modify Date: 2025-09-06 16:10:50

Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide trifluoroacetate salt structure	Common Name	Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide trifluoroacetate salt
	CAS Number	819048-44-7	Molecular Weight	1177.36000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₁H₇₂N₁₈O₁₁S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide trifluoroacetate salt

Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 is a cyclic octapeptide with MC4R agonism. Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 significantly increases heart rate and blood pressure[1].

Name	ac-d-arg-cys-glu-his-d-phe-arg-trp-cys-nh2

Description	Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 is a cyclic octapeptide with MC4R agonism. Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 significantly increases heart rate and blood pressure[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor
References	[1]. Doering SR, et al. Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign. J Med Chem. 2021 May 13;64(9):5577-5592. doi: 10.1021/acs.jmedchem.0c02041. Epub 2021 Apr 22. Erratum in: J Med Chem. 2023 May 25;66(10):7063-7065.

Molecular Formula	C₅₁H₇₂N₁₈O₁₁S₂
Molecular Weight	1177.36000
Exact Mass	1176.51000
PSA	559.06000
LogP	2.76280
InChIKey	ZUGUOZWTPYJYJW-ZSTGMXRXSA-N
SMILES	CC(=O)NC(CCCN=C(N)N)C(=O)NC(CS)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCN=C(N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CS)C(N)=O

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Product Name: AC-D-ARG-CYS-GLU-HIS-D-PHE-ARG-TRP-CYS-NH2
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Price: ￥2549/1 mg

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Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide trifluoroacetate salt

Use of Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide trifluoroacetate salt

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