N-Desethyl amodiaquine

Modify Date: 2024-01-05 10:14:21

N-Desethyl amodiaquine structure	Common Name	N-Desethyl amodiaquine
	CAS Number	79352-78-6	Molecular Weight	327.81
	Density	1.304g/cm3	Boiling Point	477.8ºC at 760 mmHg
	Molecular Formula	C₁₈H₁₈ClN₃O	Melting Point	168-174ºC
	MSDS	N/A	Flash Point	242.7ºC

Use of N-Desethyl amodiaquine

N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

Name	n-desethyl amodiaquine dihcl
Synonym	More Synonyms

Description	N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
References	[1]. Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82.

Density	1.304g/cm3
Boiling Point	477.8ºC at 760 mmHg
Melting Point	168-174ºC
Molecular Formula	C₁₈H₁₈ClN₃O
Molecular Weight	327.81
Flash Point	242.7ºC
Exact Mass	332.14500
PSA	57.18000
LogP	4.91080
Index of Refraction	1.69

Amodiaquine structure

Amodiaquine

CAS#:86-42-0

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N-Desethyl amodiaquine Structure

N-Desethyl amod...

CAS#:79352-78-6

Literature: European Journal of Clinical Pharmacology, , vol. 59, # 5-6 p. 429 - 442

4,7-Dichloroquinoline structure

4,7-Dichloroqui...

CAS#:86-98-6

2-[(Ethylamino)methyl]-4-aminophenol Dihydrochloride structure

2-[(Ethylamino)...

CAS#:86177-06-2

~%

N-Desethyl amodiaquine Structure

N-Desethyl amod...

CAS#:79352-78-6

Literature: Journal of Medicinal Chemistry, , vol. 24, # 12 p. 1471 - 1475

Precursor 3
CAS#:86-42-0 Amodiaquine CAS#:86-98-6 4,7-Dichloroqui... CAS#:86177-06-2 2-[(Ethylamino)...
DownStream 1
CAS#:79352-86-6 N-[[5-[(7-chlor...

N-Desethylamodiaquine

4-[(7-Chloro-4-quinolinyl)aMino]-2-[(ethylaMino)Methyl]phenol

N-de-ethyl amodiaquine

Desethylamodiaquine-[2H5]

4-[(7-Chloro-4-quinolyl)amino]-2-aminomethylphenol

N-Desethylamodiaquine dihydrochloride

desethylamodiaquine

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-DESETHYL AMODIAQUINE DIHCL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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