Benzamide, 4-nitro-N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-

Modify Date: 2023-01-21 12:02:52

Benzamide, 4-nitro-N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)- structure	Common Name	Benzamide, 4-nitro-N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-
	CAS Number	76129-13-0	Molecular Weight	506.50400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₆N₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	4-nitro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide

Molecular Formula	C₂₇H₂₆N₂O₈
Molecular Weight	506.50400
Exact Mass	506.16900
PSA	128.91000
LogP	4.98780

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0820000

CHEMICAL NAME :: Colchicine, N-deacetyl-N-(p-nitrobenzoyl)-

CAS REGISTRY NUMBER :: 76129-13-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C27-H26-N2-O8

MOLECULAR WEIGHT :: 506.55

WISWESSER LINE NOTATION :: L B677 MV&T&J CO1 DO1 EO1 JMVR DNW& NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 19 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981

Trimethylcolchi...

CAS#:3476-50-4

4-Nitrobenzoyl ...

CAS#:122-04-3

~66%

Benzamide, 4-ni...

CAS#:76129-13-0

Literature: Quinn, Frank R.; Beisler, John A. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 251 - 256

Precursor 2
CAS#:3476-50-4 Trimethylcolchi... CAS#:122-04-3 4-Nitrobenzoyl ...
DownStream 0

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Benzamide, 4-nitro-N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream