CK1-IN-3c

Modify Date: 2024-09-04 05:51:05

CK1-IN-3c Structure
CK1-IN-3c structure
Common Name CK1-IN-3c
CAS Number 756805-89-7 Molecular Weight 347.378
Density N/A Boiling Point N/A
Molecular Formula C19H17N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CK1-IN-3c


CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM; shows selectivity over CDK5/p25, GSK-3α/β, and DYRK1A; elicits selective cytotoxic activity against the PANC-1 cell line.

 Names

Name CK1-IN-3c

 CK1-IN-3c Biological Activity

Description CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM; shows selectivity over CDK5/p25, GSK-3α/β, and DYRK1A; elicits selective cytotoxic activity against the PANC-1 cell line.
References References 1. Karthikeyan C, et al. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2663-2667. View Related Products by Target Casein Kinase

 Chemical & Physical Properties

Molecular Formula C19H17N5O2
Molecular Weight 347.378
InChIKey FSKWVQYXXLTRRM-UHFFFAOYSA-N
SMILES COc1cc2ncnc(Nc3cc(-c4ccccc4)[nH]n3)c2cc1OC
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