(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt

Modify Date: 2024-01-11 17:35:31

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt structure	Common Name	(Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt
	CAS Number	75217-63-9	Molecular Weight	3498.747
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₅₃H₂₂₅N₄₃O₅₀S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Met(O)27)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1].

Name	(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
Synonym	More Synonyms

Description	(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met(O)27)-Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11(8):459-63.

Density	1.5±0.1 g/cm3
Molecular Formula	C₁₅₃H₂₂₅N₄₃O₅₀S
Molecular Weight	3498.747
Exact Mass	3496.610596
LogP	-7.58
Index of Refraction	1.685
Storage condition	-20°C

L-Leucinamide, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-arg inyl-L-alanyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-N-[(1S)-1-[[[(1S)-3-amino-1-[[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]carbonyl]-3-oxopropyl]amino]carbonyl ]-3-(methylsulfinyl)propyl]-

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