Phosphonic acid,P-(2-oxiranylmethyl)-, diethyl ester

Modify Date: 2024-01-08 16:23:42

Phosphonic acid,P-(2-oxiranylmethyl)-, diethyl ester Structure
Phosphonic acid,P-(2-oxiranylmethyl)-, diethyl ester structure
Common Name Phosphonic acid,P-(2-oxiranylmethyl)-, diethyl ester
CAS Number 7316-37-2 Molecular Weight 194.16500
Density 1.154g/cm3 Boiling Point 268.4ºC at 760 mmHg
Molecular Formula C7H15O4P Melting Point N/A
MSDS N/A Flash Point 130.1ºC

 Names

Name 2-(diethoxyphosphorylmethyl)oxirane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.154g/cm3
Boiling Point 268.4ºC at 760 mmHg
Molecular Formula C7H15O4P
Molecular Weight 194.16500
Flash Point 130.1ºC
Exact Mass 194.07100
PSA 57.87000
LogP 1.65130
Index of Refraction 1.44

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SZ7900000
CHEMICAL NAME :
Phosphonic acid, 2,3-epoxypropyl-, diethyl ester
CAS REGISTRY NUMBER :
7316-37-2
BEILSTEIN REFERENCE NO. :
0130726
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H15-O4-P
MOLECULAR WEIGHT :
194.19
WISWESSER LINE NOTATION :
T3OTJ B1PO&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13 gm/kg/64W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Tumorigenic - tumors at site of application
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 53,695,1974
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13 gm/kg/63W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 53,695,1974

 Synthetic Route

~92%

Phosphonic acid,P-(2-oxiranylmethyl)-, diethyl ester Structure

Phosphonic acid...

CAS#:7316-37-2

Literature: Mitula, Pawel; Wawrzenczyk, Czeslaw Arkivoc, 2012 , vol. 2012, # 4 p. 216 - 232

~80%

Phosphonic acid,P-(2-oxiranylmethyl)-, diethyl ester Structure

Phosphonic acid...

CAS#:7316-37-2

Literature: Masschelein, Kurt G. R.; Stevens, Christian V. Journal of Organic Chemistry, 2007 , vol. 72, # 24 p. 9248 - 9252

~%

Phosphonic acid,P-(2-oxiranylmethyl)-, diethyl ester Structure

Phosphonic acid...

CAS#:7316-37-2

Literature: Arbusow; Lugowkin Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 1193,1198; engl. Ausg. S. 1241, 1245

 Synonyms

EINECS 230-778-9
Glycidylphosphonic acid diethyl ester
Oxiranylmethyl-phosphonsaeure-diaethylester
oxiranylmethyl-phosphonic acid diethyl ester
diethyloxiran-2-yl-methyl-phosphonate
diethyl 2,3-epoxy-propyl-phosphonate