Aptazapine

Modify Date: 2025-08-25 14:27:19

Aptazapine Structure
Aptazapine structure
Common Name Aptazapine
CAS Number 71576-41-5 Molecular Weight 369.41400
Density N/A Boiling Point N/A
Molecular Formula C20H23N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name aptazapine maleate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C20H23N3O4
Molecular Weight 369.41400
Exact Mass 369.16900
PSA 86.01000
LogP 2.05760

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ4730325
CAS REGISTRY NUMBER :
71576-41-5
LAST UPDATED :
199512
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C16-H19-N3.C4-H4-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
43680 mg/kg/2Y-I
TOXIC EFFECTS :
Cardiac - other changes Endocrine - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32760 mg/kg/78W-I
TOXIC EFFECTS :
Cardiac - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1092 mg/kg/52W-I
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986

 Synonyms

2H,10H-Pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)benzodiazepine,1,3,4,14b-tetrahydro-2-methyl-,(+-)-,(Z)-2-butenedioate (1:1)
CGS-7525A
Aptazapine maleate (USAN)
C16H19N3.C4H4O4
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