9H-ADENINE, 9-CYCLOPENTYL-

Modify Date: 2024-01-11 16:02:36

9H-ADENINE, 9-CYCLOPENTYL- Structure
9H-ADENINE, 9-CYCLOPENTYL- structure
Common Name 9H-ADENINE, 9-CYCLOPENTYL-
CAS Number 715-91-3 Molecular Weight 203.24400
Density 1.56g/cm3 Boiling Point 440.5ºC at 760 mmHg
Molecular Formula C10H13N5 Melting Point 180-183ºC(lit.)
MSDS N/A Flash Point 220.2ºC

 Use of 9H-ADENINE, 9-CYCLOPENTYL-


9-Cyclopentyladenine is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling molecules.

 Names

Name 9-cyclopentylpurin-6-amine
Synonym More Synonyms

 9H-ADENINE, 9-CYCLOPENTYL- Biological Activity

Description 9-Cyclopentyladenine is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling molecules.
References 1. Harris DN, et al. Inhibition of adenylate cyclase in human blood platelets by 9-substituted adenine derivatives. J Cyclic Nucleotide Res. 1979;5(2):125-34.

 Chemical & Physical Properties

Density 1.56g/cm3
Boiling Point 440.5ºC at 760 mmHg
Melting Point 180-183ºC(lit.)
Molecular Formula C10H13N5
Molecular Weight 203.24400
Flash Point 220.2ºC
Exact Mass 203.11700
PSA 69.62000
LogP 2.10480
Index of Refraction 1.81

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU6255000
CHEMICAL NAME :
9H-Adenine, 9-cyclopentyl-
CAS REGISTRY NUMBER :
715-91-3
BEILSTEIN REFERENCE NO. :
0211535
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H13-N5
MOLECULAR WEIGHT :
203.28
WISWESSER LINE NOTATION :
T56 BN DN FN HNJ IZ D-AL5TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03049

 Synthetic Route

~48%

9H-ADENINE, 9-CYCLOPENTYL- Structure

9H-ADENINE, 9-C...

CAS#:715-91-3

Literature: Tuncbilek, Meral; Ates-Alagoez, Zeynep; Altanlar, Nurten; Karayel, Arzu; Oezbey, Sueheyla Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 4 p. 1693 - 1700

~34%

9H-ADENINE, 9-CYCLOPENTYL- Structure

9H-ADENINE, 9-C...

CAS#:715-91-3

Literature: Thompson, Robert D.; Secunda, Sherrie; Daly, John W.; Olsson, Ray A. Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2877 - 2882

 Synonyms

9-Cyclopentyl-9H-purin-1-amine
9H-Purin-6-amine,9-cyclopentyl
6-Amino-9-cyclopentylpurine
9-cyclopentyl-9H-purin-6-amine
9-Cyclopentyladenin
9H-ADENINE,9-CYCLOPENTYL
9-Cyclopentyladenine
9-Cyclopentyl-9H-purin-6-ylamin
9-Cyclopentyl-9H-adenine
9-cyclopentyl-9H-purin-6-ylamine
Adenine,9-cyclopentyl
N9-Cyclopentyladenine