Colominic acid sodium salt
Colominic acid sodium salt structure
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Common Name | Colominic acid sodium salt | ||
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| CAS Number | 70431-34-4 | Molecular Weight | 955.70900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C33H48N3Na3O25 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Colominic acid sodium saltColominic acid sodium salt (Polysialic acid sodium salt) could be naturally isolated from the cell wall of Escherichia coli and animals, gives a red color which has an absorption maximum at 530 nm. Colominic acid sodium salt (Polysialic acid sodium salt) possesses anti-bacterial activity[1][2]. |
| Name | trisodium,N-[(2S,3R,4S)-2-[(1R)-1,2-dihydroxyethyl]-4-hydroxy-6-(2-hydroxyethoxy)oxan-3-yl]acetamide |
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| Synonym | More Synonyms |
| Description | Colominic acid sodium salt (Polysialic acid sodium salt) could be naturally isolated from the cell wall of Escherichia coli and animals, gives a red color which has an absorption maximum at 530 nm. Colominic acid sodium salt (Polysialic acid sodium salt) possesses anti-bacterial activity[1][2]. |
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| Related Catalog | |
| In Vitro | Colominic acid (Polysialic acid) is an form of N-glycosylation with great specificity for its limited central nervous system targets, including the cell adhesion molecules neural cell adhesion molecule (NCAM) and synaptic cell adhesion molecule 1 (SynCAM1), and the receptor, neuropilin-2[2]. |
| References |
| Molecular Formula | C33H48N3Na3O25 |
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| Molecular Weight | 955.70900 |
| Exact Mass | 955.22700 |
| PSA | 454.37000 |
| Storage condition | -20°C |
| RIDADR | NONH for all modes of transport |
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An IgG monoclonal antibody to group B meningococci cross-reacts with developmentally regulated polysialic acid units of glycoproteins in neural and extraneural tissues.
J. Immunol. 138 , 4402-4407, (1987) The structurally similar polysialic acid capsules of group B meningococci and Escherichia coli K1 are poor immunogens, and attempts are currently being made to improve their immunogenicity by chemical... |
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Polysialic acid units are spatially and temporally expressed in developing postnatal rat kidney.
Proc. Natl. Acad. Sci. U. S. A. 84 , 1969-1973, (1987) We report the presence of alpha(2----8)-linked polysialic acid as detected with a monoclonal antibody outside the nervous tissue in the postnatal developing rat kidney. By immunoblot analysis, the rea... |
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Reexpression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms tumor.
Proc. Natl. Acad. Sci. U. S. A. 85 , 2999-3003, (1988) A unique structural feature of the neural cell adhesion molecule N-CAM is the presence of homopolymers of alpha (2----8)-linked sialic acid units. We have used two specific probes for the detection of... |
| Colominic acid sodium salt from Escherichia coli |
| MFCD00133197 |