Benzyl-PEG3-MS

Modify Date: 2024-01-03 11:51:20

Benzyl-PEG3-MS Structure
Benzyl-PEG3-MS structure
Common Name Benzyl-PEG3-MS
CAS Number 702701-70-0 Molecular Weight 318.38600
Density N/A Boiling Point N/A
Molecular Formula C14H22O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG3-MS


Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name methanesulfonic acid 2-[2-(2-benzyloxy-ethoxy)-ethoxy]-ethyl ester
Synonym More Synonyms

 Benzyl-PEG3-MS Biological Activity

Description Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H22O6S
Molecular Weight 318.38600
Exact Mass 318.11400
PSA 79.44000
LogP 2.29340

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

(2-{2-[2-(benzyloxy)ethoxy]ethoxy}ethyl) methanesulfonate
triethylene glycol benzyl mesyl ether