(S)-(+)-4-Amino-3-hydroxybutyric acid
(S)-(+)-4-Amino-3-hydroxybutyric acid structure
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Common Name | (S)-(+)-4-Amino-3-hydroxybutyric acid | ||
|---|---|---|---|---|
| CAS Number | 7013-05-0 | Molecular Weight | 119.119 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 374.5±32.0 °C at 760 mmHg | |
| Molecular Formula | C4H9NO3 | Melting Point | 207-212ºC | |
| MSDS | Chinese USA | Flash Point | 180.3±25.1 °C | |
Use of (S)-(+)-4-Amino-3-hydroxybutyric acidGABOB, also known as γ-Amino-β-hydroxybutyric acid, β-hydroxy-γ-aminobutyric acid, β-hydroxy-GABA, is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico. It is also an endogenous active metabolite and analogue of the neurotransmitter γ-aminobutyric acid (GABA), and for this reason, may function as a neurotransmitter itself. |
| Name | (3S)-4-amino-3-hydroxybutanoic acid |
|---|---|
| Synonym | More Synonyms |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 374.5±32.0 °C at 760 mmHg |
| Melting Point | 207-212ºC |
| Molecular Formula | C4H9NO3 |
| Molecular Weight | 119.119 |
| Flash Point | 180.3±25.1 °C |
| Exact Mass | 119.058243 |
| PSA | 83.55000 |
| LogP | -1.73 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.511 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA(C) receptors.
Bioorg. Med. Chem. Lett. 18 , 402-4, (2008) The R- and S-enantiomers of 4-amino-3-hydroxybutanoic acid (GABOB) were full agonists at human recombinant rho1 GABA(C) receptors. Their enantioselectivity (R>S) matched that reported for their agonis... |
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GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.
J. Med. Chem. 28(11) , 1612-7, (1985) (RS)-5-(Aminomethyl)-2-isoxazolin-3-ol (dihydromuscimol, DHM) is a potent 4-aminobutyric acid (GABA) agonist, the inhibitory effects of which on neurons are sensitive to the antagonist bicuculline met... |
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Formation of gamma-amino-beta-hydroxybutyric acid from 2-hydroxyputrescine in rat brain.
J. Neurochem. 51(2) , 548-51, (1988) gamma-Amino-beta-[3H]hydroxybutyric acid ([3H]-GABOB) was formed in rat brain from 2-[3H]-hydroxyputrescine that had been chemically synthesized from 2-oxoputrescine and [3H]sodium borohydride. After ... |
| 3-Hydroxy-4-aminobutyric acid |
| γ-amino-β-hydroxybutyric acid |
| (S)-4-AMINO-3-HYDROXYBUTANOIC ACID |
| 3-hydroxy-4-amino-butyric acid (GABOB) |
| 3-hydroxy-GABA |
| β-Hydroxy-GABA |
| 3-hydroxy-4-amino-butyric acid |
| Butanoic acid, 4-amino-3-hydroxy- |
| (S)-(+)-GABOB |
| acide (S)-amino-4 hydroxy-3 butanoique |
| β-Hydroxy-γ-aminobutyric acid |
| 4-Amino-3-hydroxybutanoic acid |
| (S)-(+)-Amino-3-hydroxybutanoic acid |
| g-Amino-b-hydroxybutyric Acid |
| DL-4-Amino-3-hydroxybutanoic acid |
| DL-4-Amino-3-hydroxybutyric acid |
| (S)-(+)-4-Amino-3-hydroxybutyric acid |
| MFCD00672884 |
| (±)-4-Amino-3-hydroxybutyric acid |
| γ-Amino-β-hydroxy-n-butyric acid |
| UNII:1ZHM019FLD |
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- Shanghai Nianxing Industrial Co., Ltd
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- Product Name: (S)-(+)-4-Amino-3-hydroxybutyric acid
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- ShangHai DC Chemicals Co.,Ltd
- China
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: (S)-(+)-4-amino-3-hydroxybutanoic acid
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- Purity: 98.0%
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