DGAT-3
Modify Date: 2024-01-13 17:28:57
DGAT-3 structure
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Common Name | DGAT-3 | ||
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| CAS Number | 701232-20-4 | Molecular Weight | 394.467 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 616.6±55.0 °C at 760 mmHg | |
| Molecular Formula | C22H26N4O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 326.7±31.5 °C | |
Use of DGAT-3T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.IC50 value:Target: DGAT1T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. |
| Name | 2-[4-[4-(4-amino-7,7-dimethylpyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl]acetic acid |
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| Synonym | More Synonyms |
| Description | T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.IC50 value:Target: DGAT1T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 616.6±55.0 °C at 760 mmHg |
| Molecular Formula | C22H26N4O3 |
| Molecular Weight | 394.467 |
| Flash Point | 326.7±31.5 °C |
| Exact Mass | 394.200500 |
| PSA | 110.69000 |
| LogP | 3.06 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.674 |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
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| DGAT-1 inhibitor |
| cc-141 |
| DGAT-3 |
| trans-4-(4-(4-amino-7,7-dimethyl-7h-pyrimido(4,5-b)(1,4)oxazin-6-yl)phenyl)cyclohexaneacetic acid |
| T863 |