DGAT-3 structure
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Common Name | DGAT-3 | ||
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CAS Number | 701232-20-4 | Molecular Weight | 394.467 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 616.6±55.0 °C at 760 mmHg | |
Molecular Formula | C22H26N4O3 | Melting Point | N/A | |
MSDS | USA | Flash Point | 326.7±31.5 °C |
Use of DGAT-3T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.IC50 value:Target: DGAT1T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. |
Name | 2-[4-[4-(4-amino-7,7-dimethylpyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl]acetic acid |
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Synonym | More Synonyms |
Description | T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.IC50 value:Target: DGAT1T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 616.6±55.0 °C at 760 mmHg |
Molecular Formula | C22H26N4O3 |
Molecular Weight | 394.467 |
Flash Point | 326.7±31.5 °C |
Exact Mass | 394.200500 |
PSA | 110.69000 |
LogP | 3.06 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.674 |
Storage condition | 2-8℃ |
RIDADR | NONH for all modes of transport |
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DGAT-1 inhibitor |
cc-141 |
DGAT-3 |
trans-4-(4-(4-amino-7,7-dimethyl-7h-pyrimido(4,5-b)(1,4)oxazin-6-yl)phenyl)cyclohexaneacetic acid |
T863 |