Triphosphopyridine nucleotide sodium salt hydrate

Modify Date: 2025-08-27 18:36:37

Triphosphopyridine nucleotide sodium salt hydrate structure	Common Name	Triphosphopyridine nucleotide sodium salt hydrate
	CAS Number	698999-85-8	Molecular Weight	765.38700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₇N₇NaO₁₇P₃	Melting Point	175-178ºC (dec.)(lit.)
	MSDS	USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of Triphosphopyridine nucleotide sodium salt hydrate

NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP+) and reduced (NADPH)[1][2].

Name	sodium,[[5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-oxidophosphoryl] [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Synonym	More Synonyms

Description	NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP+) and reduced (NADPH)[1][2].
Related Catalog	Research Areas >> Others
References	[1]. Carugo O, et al. NADP-dependent enzymes. I: Conserved stereochemistry of cofactor binding. Proteins. 1997;28(1):10-28. [2]. Zhao FL, et al. A genetically encoded biosensor for in vitro and in vivo detection of NADP(.). Biosens Bioelectron. 2016;77:901-906.

Description

Related Catalog

Research Areas >> Others

References

[1]. Carugo O, et al. NADP-dependent enzymes. I: Conserved stereochemistry of cofactor binding. Proteins. 1997;28(1):10-28.

[2]. Zhao FL, et al. A genetically encoded biosensor for in vitro and in vivo detection of NADP(.). Biosens Bioelectron. 2016;77:901-906.

Melting Point	175-178ºC (dec.)(lit.)
Molecular Formula	C₂₁H₂₇N₇NaO₁₇P₃
Molecular Weight	765.38700
Exact Mass	765.05700
PSA	400.87000
InChIKey	CYQLUFJYVTUUFN-WUEGHLCSSA-M
SMILES	NC(=O)c1ccc[n+](C2OC(COP(=O)([O-])OP(=O)([O-])OCC3OC(n4cnc5c(N)ncnc54)C(OP(=O)(O)O)C3O)C(O)C2O)c1.O.[Na+]
Storage condition	-20°C

MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P280-P305 + P351 + P338-P337 + P313
Hazard Codes	Xn
RIDADR	NONH for all modes of transport

Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.

PLoS ONE 10(1) , e0117842, (2015)

Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and n...

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets.

Nat. Rev. Drug Discov. 10 , 453-471, (2011)

NADPH oxidases are a family of enzymes that generate reactive oxygen species (ROS). The NOX1 (NADPH oxidase 1) and NOX2 oxidases are the major sources of ROS in the artery wall in conditions such as h...

The role of free radical generation in increasing cerebrovascular permeability.

Free Radic. Biol. Med. 51 , 967-977, (2011)

The brain endothelium constitutes a barrier to the passive movement of substances from the blood into the cerebral microenvironment, and disruption of this barrier after a stroke or trauma has potenti...

|A-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate

Triphosphopyridine nucleotide sodium salt hydrate