Endosidin 9

Modify Date: 2024-01-03 11:23:46

Endosidin 9 Structure
Endosidin 9 structure
Common Name Endosidin 9
CAS Number 693806-53-0 Molecular Weight 363.2
Density N/A Boiling Point N/A
Molecular Formula C10H7BrN2O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Endosidin 9


Endosidin 9 (ES9) is a novel mitochondrial uncoupler, and a potent inhibitor of clathrin-mediated endocytosis (CME) in different systems, strongly reduces FM4-64 uptake in Arabidopsis root cells with IC50 of 5 uM.Endosidin 9 (ES9) inhibits CME dynamics and organelle movement in the cytoplasm.Endosidin9 (ES9) inhibits clathrin-mediated endocytosis largely through cytoplasmic acidification.

 Names

Name Endosidin 9

 Endosidin 9 Biological Activity

Description Endosidin 9 (ES9) is a novel mitochondrial uncoupler, and a potent inhibitor of clathrin-mediated endocytosis (CME) in different systems, strongly reduces FM4-64 uptake in Arabidopsis root cells with IC50 of 5 uM.Endosidin 9 (ES9) inhibits CME dynamics and organelle movement in the cytoplasm.Endosidin9 (ES9) inhibits clathrin-mediated endocytosis largely through cytoplasmic acidification.
References 1. Dejonghe W, et al. Nat Chem Biol. 2019 Jun;15(6):641-649. 2. Dejonghe W, et al. Nat Commun. 2016 Jun 8;7:11710.

 Chemical & Physical Properties

Molecular Formula C10H7BrN2O4S2
Molecular Weight 363.2