Inh2-B1
Modify Date: 2025-09-23 14:00:29
Inh2-B1 structure
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Common Name | Inh2-B1 | ||
|---|---|---|---|---|
| CAS Number | 690216-38-7 | Molecular Weight | 411.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H13N3O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Inh2-B1Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA. |
| Name | Inh2-B1 |
|---|
| Description | Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA. |
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| References | References 1. Kant S, et al. Sci Rep. 2017 Jul 11;7(1):5067. View Related Products by Target Bacterial |
| Molecular Formula | C19H13N3O4S2 |
|---|---|
| Molecular Weight | 411.45 |
| InChIKey | WKFXKJMYGNYRPR-UHFFFAOYSA-N |
| SMILES | COC(=O)c1ccc2c(=O)[nH]c3c(C(=O)Nc4ccccc4)sc(=S)n3c2c1 |