4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol

Modify Date: 2025-08-25 19:39:52

4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol Structure
4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol structure
 Common Name 4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol
CAS Number 681482-81-5 Molecular Weight 353.33600
Density N/A Boiling Point N/A
Molecular Formula C18H18F3NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C18H18F3NO3
Molecular Weight 353.33600
Exact Mass 353.12400
PSA 41.93000
LogP 4.40360
Storage condition 2-8°C

 Synthetic Route

1-(4-benzyloxy-phenyl)-4-(4-trifluoromethoxy-phenoxy)-piperidine structure

1-(4-benzyloxy-...

CAS#:1083099-55-1

~99%

4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol Structure

4-[4-[4-(triflu...

CAS#:681482-81-5

Literature: OTSUKA PHARMACEUTICAL CO., LTD. Patent: WO2008/140090 A1, 2008 ; Location in patent: Page/Page column 42-43 ;
1,4-Cyclohexanedione structure

1,4-Cyclohexanedione

CAS#:637-88-7

4-(4-Trifluoromethoxyphenoxy)piperidine structure

4-(4-Trifluorom...

CAS#:287952-67-4

~89%

4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol Structure

4-[4-[4-(triflu...

CAS#:681482-81-5

Literature: OTSUKA PHARMACEUTICAL CO., LTD. Patent: WO2005/92832 A1, 2005 ; Location in patent: Page/Page column 48-49 ;
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine structure

1-[4-(tetrahydr...

CAS#:681482-80-4

~91%

4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol Structure

4-[4-[4-(triflu...

CAS#:681482-81-5

Literature: Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860
Phenol, 4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]-, 4-Methylbenzenesulfonate (salt) structure

Phenol, 4-[4-[4...

CAS#:866109-93-5

~96%

4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol Structure

4-[4-[4-(triflu...

CAS#:681482-81-5

Literature: OTSUKA PHARMACEUTICAL CO., LTD. Patent: WO2008/140090 A1, 2008 ; Location in patent: Page/Page column 34-35; 36-37 ;
2-(4-Bromophenoxy)tetrahydro-2H-pyran structure

2-(4-Bromopheno...

CAS#:36603-49-3

~%

4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol Structure

4-[4-[4-(triflu...

CAS#:681482-81-5

Literature: Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860
4-(4-Trifluoromethoxyphenoxy)piperidine structure

4-(4-Trifluorom...

CAS#:287952-67-4

~%

4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol Structure

4-[4-[4-(triflu...

CAS#:681482-81-5

Literature: Sasaki, Hirofumi; Haraguchi, Yoshikazu; Itotani, Motohiro; Kuroda, Hideaki; Hashizume, Hiroyuki; Tomishige, Tatsuo; Kawasaki, Masanori; Matsumoto, Makoto; Komatsu, Makoto; Tsubouchi, Hidetsugu Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7854 - 7860

 Synonyms

ss-3227
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Chemsrc provides CAS#:681482-81-5 MSDS, density, melting point, boiling point, structure, etc. Its name is 4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol>> amp version: 4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenol

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