Platyconic acid A

Modify Date: 2025-08-25 13:23:56

Platyconic acid A Structure
Platyconic acid A structure
Common Name Platyconic acid A
CAS Number 68051-23-0 Molecular Weight 1239.307
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C57H90O29 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Platyconic acid A


Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation[1].

 Names

Name Platyconic acid A
Synonym More Synonyms

 Platyconic acid A Biological Activity

Description Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation[1].
Related Catalog
In Vitro Platyconic Acid A (0.5~2 μM; 30 minutes; A549 cells) inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner[1]. Platyconic Acid A (0.5~2 μM; 24 hours; A549 cells) decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner[1]. Western Blot Analysis[1] Cell Line: A549 cells Concentration: 0.5~2 μM Incubation Time: 30 minutes Result: Inhibited PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner. RT-PCR[1] Cell Line: A549 cells Concentration: 0.5~2 μM Incubation Time: 24 hours Result: Decreased PMA-increased MUC5AC mRNA expression in a concentration-dependent manner.
References

[1]. Choi JH, et al. Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells. J Agric Food Chem. 2015;63(5):1468-1476.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C57H90O29
Molecular Weight 1239.307
Exact Mass 1238.556763
LogP -0.36
Index of Refraction 1.663

 Synonyms

PLATYCONIC ACID A
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