Arterolane
Modify Date: 2025-12-01 20:43:32
Arterolane structure
|
Common Name | Arterolane | ||
|---|---|---|---|---|
| CAS Number | 664338-39-0 | Molecular Weight | 392.53200 | |
| Density | 1.202 g/cm3 | Boiling Point | 572.161ºC at 760 mmHg | |
| Molecular Formula | C22H36N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 299.832ºC | |
Use of ArterolaneArterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively. |
| Name | Arterolane |
|---|---|
| Synonym | More Synonyms |
| Description | Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.1 nM (P. falciparum Ro73), 1.1 nM (P. falciparum W2)[1] |
| In Vitro | Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC50s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. Arterolane also shows inhibitory activity against several other P. falciparums, with IC50s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively[1]. |
| References |
| Density | 1.202 g/cm3 |
|---|---|
| Boiling Point | 572.161ºC at 760 mmHg |
| Molecular Formula | C22H36N2O4 |
| Molecular Weight | 392.53200 |
| Flash Point | 299.832ºC |
| Exact Mass | 392.26800 |
| PSA | 86.30000 |
| LogP | 4.78790 |
| InChIKey | VXYZBLXGCYNIHP-UHFFFAOYSA-N |
| SMILES | CC(C)(N)CNC(=O)CC1CCC2(CC1)OOC1(O2)C2CC3CC(C2)CC1C3 |
| Storage condition | 2-8℃ |
| oz277 |
| unii-3n1tn351vb |