Methotrexate alpha-Methyl Ester

Modify Date: 2024-01-11 23:17:24

Methotrexate alpha-Methyl Ester Structure
Methotrexate alpha-Methyl Ester structure
Common Name Methotrexate alpha-Methyl Ester
CAS Number 66147-29-3 Molecular Weight 468.46600
Density N/A Boiling Point N/A
Molecular Formula C21H24N8O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methotrexate alpha-Methyl Ester


Methotrexate 1-methyl ester is an impurity of Methotrexate, a folic acid antagonist. Used as a antineoplastic and antirheumatic.

 Names

Name (4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C21H24N8O5
Molecular Weight 468.46600
Exact Mass 468.18700
PSA 200.27000
LogP 1.25900

 Synonyms

Methotrexate 1-methyl ester
Methotrexate related compound I [USP]
L-Glutamic acid,N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-,1-methyl ester
(4S)-4-((4-(((2,4-Diaminopteridin-6-yl)methyl)methylamino)benzoyl)amino)-5-methoxy-5-oxopentanoic acid
Methotrexate related compound I
UNII-5NL2U9S7K1
Methotrexate specified impurity I [EP]
Methotrexate alpha-Methyl Ester
Methotrexate α-Methyl Ester