Colchinol, N-acetyl-, methyl ether

Modify Date: 2024-01-08 10:17:30

Colchinol, N-acetyl-, methyl ether Structure
Colchinol, N-acetyl-, methyl ether structure
Common Name Colchinol, N-acetyl-, methyl ether
CAS Number 65967-01-3 Molecular Weight 371.42700
Density 1.21g/cm3 Boiling Point 599ºC at 760 mmHg
Molecular Formula C21H25NO5 Melting Point N/A
MSDS N/A Flash Point 316.1ºC

 Names

Name N-(1,2,3,9-tetramethoxy-6,7-dihydro-5H-dibenzo[5,3-b:1',2'-e][7]annulen-7-yl)acetamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.21g/cm3
Boiling Point 599ºC at 760 mmHg
Molecular Formula C21H25NO5
Molecular Weight 371.42700
Flash Point 316.1ºC
Exact Mass 371.17300
PSA 66.02000
LogP 3.90230
Index of Refraction 1.581

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GH1008000
CHEMICAL NAME :
Colchinol, N-acetyl-, methyl ether
CAS REGISTRY NUMBER :
65967-01-3
LAST UPDATED :
199409
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H25-N-O5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 85,235,1920
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
320 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 85,235,1920

 Synthetic Route

 Synonyms

(-)-N-acetylcochinol methyl ether
(S)-N-acetyl-O-methyl-colchinol
(S)-N-acetyl-O-methyl-colchicinol
Acetamide,N-(6,7-dihydro-3,9,10,11-tetramethoxy-5H-dibenzo(a,c)cyclohepten-5-yl)-,(S)
N-Azetyl-colchinol-methylaether [German]
Colchinol,N-acetyl-,methyl ether
N-acetylallocolchinol O-methyl ether
N-Acetylcolchinol methyl ether
N-Acetylcolchinol O-methyl ether
N-acetylcolchcinol methyl ester