1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos

Modify Date: 2024-01-02 10:40:07

1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos Structure
1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos structure
Common Name 1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos
CAS Number 653600-56-7 Molecular Weight 430.37
Density N/A Boiling Point N/A
Molecular Formula C16H22N4O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos


Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Ac4GalNAz

  Biological Activity

Description Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H22N4O10
Molecular Weight 430.37
Storage condition 2-8℃
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