STING Agonist 1a
Modify Date: 2025-08-28 10:01:47
STING Agonist 1a structure
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Common Name | STING Agonist 1a | ||
|---|---|---|---|---|
| CAS Number | 652142-94-4 | Molecular Weight | 396.229 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C19H11Cl2N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STING Agonist 1aSTING agonist-16 (1a) is a specific stimulator of interferon genes (STING) agonist. STING agonist-16 (1a) can be used as a potential antiviral and antitumor tool[1]. |
| Name | STING Agonist 1a |
|---|---|
| Synonym | More Synonyms |
| Description | STING agonist-16 (1a) is a specific stimulator of interferon genes (STING) agonist. STING agonist-16 (1a) can be used as a potential antiviral and antitumor tool[1]. |
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| Related Catalog | |
| In Vitro | STING agonist-16 (1a) (0-100 μM, 6 h) can promote mRNA expression of IFNβ, CXCL-10 and IL-6 in a dose-dependent manner with no significant cytotoxic effect up to 100 μM in human myeloid leukemia mononuclear cells (THP1)[1]. STING agonist-16 (1a) (50 μM, 2 h) significantly induces the phosphorylation of STING, TANK-binding kinases1 (TBK1) and interferon regulatory factor 3 (IRF3) in THP1 cells[1]. STING agonist-16 (1a) activates secretory alkaline phosphatase (SEAP) in a dose-dependent manner with an EC50 value of 16.77 μM while 2'3'-cGAMP acts with an EC50 value of 9.212 μM[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C19H11Cl2N5O |
| Molecular Weight | 396.229 |
| Exact Mass | 395.034058 |
| LogP | 4.40 |
| Index of Refraction | 1.772 |
| 4-Chloro-1-(2-chloro-6-methoxy-3-quinolinyl)[1,2,4]triazolo[4,3-a]quinoxaline |
| [1,2,4]Triazolo[4,3-a]quinoxaline, 4-chloro-1-(2-chloro-6-methoxy-3-quinolinyl)- |
| MFCD03861727 |
| STING Agonist 1a |