α-Cyclohexyl-α-hydroxybenzeneacetic acid 1-ethyl-3-piperidinyl ester

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C21-H31-N-O3

MOLECULAR WEIGHT :

345.53

WISWESSER LINE NOTATION :

T6NTJ A2 COVXQR&- AL6TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

20 mg/kg

TOXIC EFFECTS :

Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

37 mg/kg

TOXIC EFFECTS :

Behavioral - muscle weakness Behavioral - ataxia Cardiac - pulse rate increase, without fall in BP

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 120,186,1959