MAT2A-IN-12

MAT2A-IN-12 structure	Common Name	MAT2A-IN-12
	CAS Number	631897-75-1	Molecular Weight	319.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₇NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MAT2A-IN-12

MAT2A Allosteric inhibitor 2 is a potent and selective MAT2A allosteric inhibitor with an IC50 of 5 nM. MAT2A Allosteric inhibitor 2 shows nanomolar activity (IC50=5 μM) in the the proliferation assay (MTAP-/- cell line)[1].

Name	MAT2A-IN-12

Description	MAT2A Allosteric inhibitor 2 is a potent and selective MAT2A allosteric inhibitor with an IC50 of 5 nM. MAT2A Allosteric inhibitor 2 shows nanomolar activity (IC50=5 μM) in the the proliferation assay (MTAP-/- cell line)[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Tuomo Kalliokoski, et al. Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorg Med Chem Lett . 2023 Oct 1;94:129450

Molecular Formula	C₂₀H₁₇NO₃
Molecular Weight	319.35

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