JYL-1511
Modify Date: 2025-08-25 20:03:40
JYL-1511 structure
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Common Name | JYL-1511 | ||
|---|---|---|---|---|
| CAS Number | 623166-14-3 | Molecular Weight | 435.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H29N3O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JYL-1511JYL 1511 is a partial agonist of vanilloid receptor VR1[1]. |
| Name | 1-[(4-tert-butylphenyl)methyl]-3-[[4-(methanesulfonamido)-3-methoxyphenyl]methyl]thiourea |
|---|---|
| Synonym | More Synonyms |
| Description | JYL 1511 is a partial agonist of vanilloid receptor VR1[1]. |
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| Related Catalog | |
| In Vitro | JYL 1511 抑制 [3H]Resiniferatoxin 与大鼠 VR1 的结合，Ki 为 50.4 nM[1]。 JYL 1511 抑制过表达大鼠 VR1 的 CHO 细胞中辣椒素诱导的 45Ca2+ 摄取 (IC50: 3.4 nM)[1]. |
| References |
| Molecular Formula | C21H29N3O3S2 |
|---|---|
| Molecular Weight | 435.60 |
| Exact Mass | 435.16500 |
| PSA | 119.93000 |
| LogP | 5.46410 |
| JYL-1511 |
| Methanesulfonamide,N-(4-((((((4-(1,1-dimethylethyl)phenyl)methyl)amino)thioxomethyl)amino)methyl)-2-methoxyphenyl) |
| thiourea analogue,3 |
| UNII-9MD3654O9N |