phosphocyclocreatine

Modify Date: 2025-09-13 12:09:15

phosphocyclocreatine Structure
phosphocyclocreatine structure
Common Name phosphocyclocreatine
CAS Number 61839-19-8 Molecular Weight 223.12400
Density 2.03g/cm3 Boiling Point 481ºC at 760 mmHg
Molecular Formula C5H10N3O5P Melting Point N/A
MSDS N/A Flash Point 244.7ºC

 Use of phosphocyclocreatine


Cyclocreatine phosphate is an anti-tumor agent. Cyclocreatine phosphate is the proposed active form of cyclocreatine (CCr), a substrate analogue of creatine kinase. Cyclocreatine phosphate has anti-tumour activity and can be used for the research of cancer[1].

 Names

Name 2-(2-imino-3-phosphonoimidazolidin-1-yl)acetic acid
Synonym More Synonyms

 phosphocyclocreatine Biological Activity

Description Cyclocreatine phosphate is an anti-tumor agent. Cyclocreatine phosphate is the proposed active form of cyclocreatine (CCr), a substrate analogue of creatine kinase. Cyclocreatine phosphate has anti-tumour activity and can be used for the research of cancer[1].
Related Catalog
In Vivo Cyclocreatine phosphate (CCr'P) (i.p.; 37.5 mg/mL; 0.2 mL, twice daily) has anti-tumor activity without any notable signs of toxicity in a mouse xenograft model for human prostate cancer[1]. Animal Model: Athymic (CDl-Nu/Nu) male mice[1] Dosage: 37.5 mg/mL Administration: intraperitoneally , 0.2 mL, twice daily Result: Showed anti-tumor effect.
References

[1]. Rima Kaddurah-Daouk, et al. Creatine phosphate, creatine phosphate analogs, and uses therefor. Patent. WO1994016712A1.

 Chemical & Physical Properties

Density 2.03g/cm3
Boiling Point 481ºC at 760 mmHg
Molecular Formula C5H10N3O5P
Molecular Weight 223.12400
Flash Point 244.7ºC
Exact Mass 223.03600
PSA 134.97000
Index of Refraction 1.733

 Synonyms

Phosphocyclocreatine
N-Phosphorylcyclocreatine
[(2e)-2-imino-3-phosphonoimidazolidin-1-yl]acetic acid
Cyclocreatine phosphate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.