CTPB

Modify Date: 2024-01-08 20:10:06

Use of CTPB

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1].

Name	N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecylbenzamide
Synonym	More Synonyms

Description	CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Acetyltransferase
Target	p300
In Vitro	CTPB is a synthetic HAT activator, which promotes the transcription by increasing the H3 and H4 acetylation in nucleosome[1].
References	[1]. Sivanandam M, et al. Investigation of activation mechanism and conformational stability of N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxybenzamide and N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamidein the active site of p300 histone acetyl transferase enzyme by molecular dynamics and binding free-energy studies. J Biomol Struct Dyn. 2018 Oct 9:1-38.

RIDADR	NONH for all modes of transport

ctpb

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