1α-Hydroxy-3-epi-vitamin D3

Modify Date: 2025-09-05 16:58:19

1α-Hydroxy-3-epi-vitamin D3 Structure
1α-Hydroxy-3-epi-vitamin D3 structure
Common Name 1α-Hydroxy-3-epi-vitamin D3
CAS Number 58028-00-5 Molecular Weight 400.64
Density N/A Boiling Point N/A
Molecular Formula C27H44O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1α-Hydroxy-3-epi-vitamin D3


1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion[1].

 Names

Name 1α-Hydroxy-3-epi-vitamin D3

 1α-Hydroxy-3-epi-vitamin D3 Biological Activity

Description 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion[1].
Related Catalog
In Vitro 1 alpha, 25(OH)2D3 is an important negative regulator of parathyroid hormone (PTH) gene transcription[1]. In ROS 17/2.8 cells, 1α-OHD3 (10 μM) not only metabolized into 1αOH-3-epi-D3 and 1α,25(OH)2D3 but also 1α,25(OH)2-3-epi-D3[2].
References

[1]. A J Brown, et al. 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion. J Cell Biochem. 1999 Apr 1;73(1):106-13.

[2]. Alex J Brown, et al. Isolation and identification of 1alpha-hydroxy-3-epi-vitamin D3, a potent suppressor of parathyroid hormone secretion. J Cell Biochem

 Chemical & Physical Properties

Molecular Formula C27H44O2
Molecular Weight 400.64
InChIKey OFHCOWSQAMBJIW-NIZRVZOPSA-N
SMILES C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)C)CC(O)CC1O
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