Ethacizine hydrochloride
Modify Date: 2025-08-25 07:55:57
Ethacizine hydrochloride structure
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Common Name | Ethacizine hydrochloride | ||
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| CAS Number | 57530-40-2 | Molecular Weight | 449.99400 | |
| Density | N/A | Boiling Point | 576.7ºC at 760mmHg | |
| Molecular Formula | C22H28ClN3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 302.6ºC | |
Use of Ethacizine hydrochlorideEthacizine hydrochloride (Ethacizin; NIK-244) is a longer-lasting Class Ic antiarrhythmic agent than Flecainide[1]. Ethacizine hydrochloride (Ethacizin; NIK-244) inhibits the depolarizing current responsible for the intraatrial and His-Purkinje-ventricular conduction[2]. |
| Name | ethyl N-[10-[3-(diethylamino)propanoyl]phenothiazin-2-yl]carbamate,hydrochloride |
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| Synonym | More Synonyms |
| Description | Ethacizine hydrochloride (Ethacizin; NIK-244) is a longer-lasting Class Ic antiarrhythmic agent than Flecainide[1]. Ethacizine hydrochloride (Ethacizin; NIK-244) inhibits the depolarizing current responsible for the intraatrial and His-Purkinje-ventricular conduction[2]. |
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| Related Catalog | |
| In Vivo | NIK-244 (1-300 ug) injects directly into the SA node and PM preparations shows negative chronotropic, negative inotropic and coronary vasodilator[1]. |
| References |
| Boiling Point | 576.7ºC at 760mmHg |
|---|---|
| Molecular Formula | C22H28ClN3O3S |
| Molecular Weight | 449.99400 |
| Flash Point | 302.6ºC |
| Exact Mass | 449.15400 |
| PSA | 90.67000 |
| LogP | 5.99680 |
| InChIKey | VHNXQKLWIQHSOY-UHFFFAOYSA-N |
| SMILES | CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN(CC)CC)c1ccccc1S2.Cl |
| Ethacizine hydrochloride |