3-hydroxybenzothiophene-2-carbonitrile

Modify Date: 2024-01-05 17:20:03

3-hydroxybenzothiophene-2-carbonitrile Structure
3-hydroxybenzothiophene-2-carbonitrile structure
Common Name 3-hydroxybenzothiophene-2-carbonitrile
CAS Number 57477-69-7 Molecular Weight 175.20700
Density 1.44g/cm3 Boiling Point 379.1ºC at 760 mmHg
Molecular Formula C9H5NOS Melting Point N/A
MSDS N/A Flash Point 183.1ºC

 Names

Name 3-hydroxy-1-benzothiophene-2-carbonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.44g/cm3
Boiling Point 379.1ºC at 760 mmHg
Molecular Formula C9H5NOS
Molecular Weight 175.20700
Flash Point 183.1ºC
Exact Mass 175.00900
PSA 72.26000
LogP 2.47858
Index of Refraction 1.73

 Synthetic Route

~56%

3-hydroxybenzothiophene-2-carbonitrile Structure

3-hydroxybenzot...

CAS#:57477-69-7

Literature: Sugiyama, Hideyuki; Yoshida, Masato; Mori, Kouji; Kawamoto, Tomohiro; Sogabe, Satoshi; Takagi, Terufumi; Oki, Hideyuki; Tanaka, Toshimasa; Kimura, Hiroyuki; Ikeura, Yoshinori Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 4 p. 613 - 624

~82%

3-hydroxybenzothiophene-2-carbonitrile Structure

3-hydroxybenzot...

CAS#:57477-69-7

Literature: Hirota, Takashi; Tomita, Kei-Ichiroh; Sasaki, Kenji; Okuda, Kensuke; Yoshida, Masahiko; Kashino, Setsuo Heterocycles, 2001 , vol. 55, # 4 p. 741 - 752

~88%

3-hydroxybenzothiophene-2-carbonitrile Structure

3-hydroxybenzot...

CAS#:57477-69-7

Literature: Rackham, Mark D.; Brannigan, James A.; Rangachari, Kaveri; Meister, Stephan; Wilkinson, Anthony J.; Holder, Anthony A.; Leatherbarrow, Robin J.; Tate, Edward W. Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2773 - 2788

~%

3-hydroxybenzothiophene-2-carbonitrile Structure

3-hydroxybenzot...

CAS#:57477-69-7

Literature: Sugiyama, Hideyuki; Yoshida, Masato; Mori, Kouji; Kawamoto, Tomohiro; Sogabe, Satoshi; Takagi, Terufumi; Oki, Hideyuki; Tanaka, Toshimasa; Kimura, Hiroyuki; Ikeura, Yoshinori Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 4 p. 613 - 624

~%

3-hydroxybenzothiophene-2-carbonitrile Structure

3-hydroxybenzot...

CAS#:57477-69-7

Literature: Hirota, Takashi; Tomita, Kei-Ichiroh; Sasaki, Kenji; Okuda, Kensuke; Yoshida, Masahiko; Kashino, Setsuo Heterocycles, 2001 , vol. 55, # 4 p. 741 - 752

~%

3-hydroxybenzothiophene-2-carbonitrile Structure

3-hydroxybenzot...

CAS#:57477-69-7

Literature: Sasaki; Tashima; Nakayama; Hirota Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 2 p. 269 - 272

 Synonyms

2-Cyano-3-hydroxy-benzo<b>thiophen
3-hydroxybenzothiophene-2-carbonitrile
2-Cyano-3-hydroxybenzo<4.5>thiophen
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