4-N-methyl-7H-pyrimido[4,5-b][1,4]thiazine-4,6-diamine

MOLECULAR FORMULA :

C7-H9-N5-S

MOLECULAR WEIGHT :

195.27

WISWESSER LINE NOTATION :

T66 BN DN GN JS IHJ EM1 HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

350 mg/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

REFERENCE :

PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,1205,1977